东盟疫苗能力调查（AVCS）-评估报告-2025.1_29页_858kb

ASEAN Vaccine Capacity Survey (AVCS) Assessment Report Summary

Introduction

The AVCS is a comprehensive assessment of vaccine capabilities in ASEAN member countries, supporting the ASEAN Vaccine Security and Self-Reliance (AVSSR) plan to enhance regional self-sufficiency and collaboration in vaccines. It builds on previous surveys, using primary and secondary data collection methods, to guide policy implementation and improve access to affordable, quality-assured vaccines across the region.

Methodology

Data was gathered through an Excel template, web resources, teleconferences, and expert interviews, focusing on areas like vaccine access, funding mechanisms, national immunisation programs, regulatory frameworks, and crisis management. This multi-faceted approach ensures a holistic view for informed decision-making.

Key Findings

• Vaccine Access and Decision Making: Countries employ diverse mechanisms involving health ministries, advisory groups, and funding sources like GAVI, ensuring organized vaccine introduction and availability.
• Funding Mechanisms: Member states invest in vaccination subsidies, COVID-19 research, epidemic preparedness, and procurement systems, with some receiving international support to strengthen supply chains.
• National Immunisation Programme (NIP) and AEFI Monitoring: Communicable diseases like Dengue and Tuberculosis are prominent, with robust AEFI surveillance systems ensuring vaccine safety through collaborations and real-time monitoring.
• Stockpiling and Supply Chain: Centralized supply chain management facilitates efficient distribution, with variations in logistics, often augmented by digital systems for traceability.
• Human Resource Development: Training is available for healthcare workers, but targeted HRD plans for vaccine occupations are needed to build a skilled workforce.
• National Regulatory Authority (NRA) and National Control Laboratory (NCL): All member states have NRAs ensuring medical product safety and quality; six have NCLs, with commitments to international standards like GMP.
• Local Vaccine R&D: Three countries conduct vaccine R&D, supported by facilities for animal testing and human trials, fostering innovation and global collaboration.
• Vaccine Production: Two member states actively produce vaccines, with private and public sectors collaborating through partnerships to enhance manufacturing capacity.
• Challenges: Limitations in R&D infrastructure, insufficient educational programs, workforce shortages, and lack of local production facilities need addressing to improve vaccine resilience.

Recommendations

• Strengthen training in vaccine R&D, production, and regulatory affairs to ensure quality and safety.
• Promote technology transfer, adequate funding, and public investment to support innovation and self-reliance.
• Implement buffer stocks for recommended vaccines and contingency plans for emergencies.
• Foster regional partnerships and collaborations with international organizations to share resources and expertise.

Conclusion

The AVCS demonstrates ASEAN's commitment to vaccine security and self-reliance, highlighting both strengths and challenges in the region's vaccine landscape. Continued collaboration and investment are essential for enhancing capabilities and responding effectively to global health threats.